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The Convent was built in 1510, by the Piccolimini for the Franciscan friars who had lost their ancient seat. The building has a square plan, masonry structure and linear shapes; it develops on two floors, connected by a wide staircase, and boasts an elegant cloister with central well.
The church, commissioned by the Marquises Piccolomini, was completed in 1660, more than a century after the construction of the adjoining convent. It was called gentilitia because the Piccolomini here had their own "seat of honor", received the sacraments of Baptism and Marriage, and were buried near the high altar. It is Baroque with a facade covered in stone, with a beautiful carved stone portal and door in bronze panels with the miracles of Sant'Antonio, made in 1981 on a design by the artist delicetano Gerardo Liberti and sketches by Gerardo Maraschiello. The façade includes a bell tower with a clock.
The interior has three naves with six side chapels and under the vault you can appreciate the painted image of the Immaculate Conception of the delicetano M. Nigro. In the second chapel on the right is a painting by Benedetto Brunetti depicting Our Lady of Sorrows between Saint Francis and Pope Pius II (1646), while in a niche above the high altar is the wooden statue of Saint Anthony in Spanish style, with a flower-inlaid robe, on a base of pure gold. The pipe organ, perfectly preserved on the church choir, was made in the late eighteenth century by Domenico Antonio Rossi, organist of the Royal Chapel of Naples.
